Thursday, May 2, 2013

As South Korea and US end military drills, how will North Korea react?

Many Korea watchers speculated that once joint military drills ended, so would increased tensions with North Korea. But at least one analyst says this might be the moment the North lashes out again.?

By Steven Borowiec,?Correspondent / April 30, 2013

US military vehicles cross Unification bridge, which leads to the demilitarized zone separating North Korea from South Korea near the border village of Panmunjom in Paju, South Korea, Tuesday. The US-South Korean annual military drills ended Tuesday without incident.

Ahn Young-joon/AP

Enlarge

The US-South Korea annual military exercises ended without incident on Tuesday, perhaps allowing a chance for weeks of tensions on the Korean peninsula to enter an indefinite period of calm.

Skip to next paragraph Steven Borowiec

Korea Correspondent

Since 2009, Steven Borowiec has reported from Seoul, South Korea on politics, socio-economics, and culture. He is a deputy editor at South Korea?s Hankyoreh newspaper and a features writer for Yonhap News Agency.?

Recent posts

' + google_ads[0].line2 + '
' + google_ads[0].line3 + '

'; } else if (google_ads.length > 1) { ad_unit += ''; } } document.getElementById("ad_unit").innerHTML += ad_unit; google_adnum += google_ads.length; return; } var google_adnum = 0; google_ad_client = "pub-6743622525202572"; google_ad_output = 'js'; google_max_num_ads = '1'; google_feedback = "on"; google_ad_type = "text"; google_adtest = "on"; google_image_size = '230x105'; google_skip = '0'; // -->

The annual military defensive exercises are intended to act as a deterrent to North Korea through shows of military prowess.?North Korea, however, called the two month-long exercises an aggressive invasion threat and promised military retaliation if provoked directly.

But now that the exercises are over, the North could tell its people that its own military successfully warded off the threat, conceivably allowing it enter dialogue with the South without appearing to lose face.?But some analysts argue that as the general atmosphere has cooled, action by North Korea could actually be more likely.

?Now that the exercises are over, this is an opportune time for a missile launch,? says Sung-yoon Lee, professor at the Fletcher School of Law and Diplomacy, Tufts University. ?Now that their adversaries have their guard down, they could go ahead with a launch now, ahead of the upcoming summit between Obama and Park Geun-hye, to put pressure on Park.?

South Korean President Park Geun-hye, who was inaugurated on Feb. 25, is scheduled to meet with US President Obama in Washington on May 7. North Korea has been known to purposely raise tensions in an effort to rattle new administrations in Seoul or Washington.?

"The drill is over, but the South Korean and US militaries will continue to watch out for potential provocations by the North, including a missile launch," said Kim Min-seok, a spokesperson for South Korea?s Ministry of National Defense.

The two-month long exercises started up shortly after the North's third nuclear test in February and involved around 10,000 US troops and 200,000 South Korean forces. Throughout the exercises, some impressive weaponry was shown off, including B-52 bombers and a nuclear-armed submarine. After the exercises began, the North announced it was scrapping an armistice agreement that effectively put the Korean War on hold, and said it was?entering a "state of war." The North also cut two hotlines to South Korea, symbols of North-South cooperation, but left a joint economic region alone until April.?

The jointly-operated Kaesong industrial park, the last major symbol of cooperation between South and North?was designed to economically benefit both sides, providing South Korean companies with cheap labor, and North Koreans with much needed income. Since it was started in 2004, it has survived years of chilly inter-Korean relations.?

But North Korea unexpectedly barred South Koreans from entering the area early in April and then withdrew all its workers shortly thereafter. Though some South Korean workers stayed at the complex, many went back to South Korea.

The situation at Kaesong is one aspect of the crisis that appears set to continue.

Yesterday, 43 of the final 50 South Korean workers in Kaesong returned home. Seven stayed behind to deal with some unpaid wages, as North Korea has not approved their departure yet, according to Chosun. There is not yet any indication that Seoul and Pyongyang will cooperate in finding a way to get operations at the complex back underway. The complex brought in about $80 million in revenue for North Korea in 2012, so there is a large financial incentive for the North to restart business there.?

Today South Korean Minister of Unification Ryoo Kihl-jae said that while the South is interested in restarting operations at Kaesong, Seoul wouldn?t accept just any conditions demanded by North Korea.

"It is pointless to normalize operations at the Kaesong Industrial Complex if it entails accepting unreasonable claims and preconditions," Minister Ryoo said.

All throughout the war games, many analysts speculated that North Korea?s intention was to stir tensions and pull back at the last minute from any kind of engagement in an effort to strengthen its bargaining position when it returns to the table at some later date.?

?The general principle is to escalate tensions in order to later be able to negotiate from a position of strength,? Leonid Petrov, a researcher in Korean studies at Australian National University, told the Monitor on Apr. 10.

Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/mCw340oEnTc/As-South-Korea-and-US-end-military-drills-how-will-North-Korea-react

andrew breitbart dead sheriff joe arpaio limbaugh aaron smith wilt chamberlain joe arpaio cat in the hat

Wednesday, May 1, 2013

Orb made 7-2 favorite for Kentucky Derby

Exercise rider Jenn Patterson rides Kentucky Derby entrant Orb for a workout at Churchill Downs Monday, April 29, 2013, in Louisville, Ky. (AP Photo/Garry Jones)

Exercise rider Jenn Patterson rides Kentucky Derby entrant Orb for a workout at Churchill Downs Monday, April 29, 2013, in Louisville, Ky. (AP Photo/Garry Jones)

Exercise rider Humberto Zamora rides Kentucky Derby hopeful Verrazano for a workout at Churchill Downs Wednesday, May 1, 2013, in Louisville, Ky. (AP Photo/Morry Gash)

Trainer Todd Pletcher watches morning workouts at Churchill Downs Wednesday, May 1, 2013, in Louisville, Ky. (AP Photo/Garry Jones)

An exercise rider takes Kentucky Derby hopeful Itsmyluckyday for a workout at Churchill Downs Wednesday, May 1, 2013, in Louisville, Ky. (AP Photo/Garry Jones)

Part-owner of Kentucky Derby hopeful Goldencents Rick Pitino, left, talks to jockey Kevin Krigger at Churchill Downs Wednesday, May 1, 2013, in Louisville, Ky. (AP Photo/Garry Jones)

(AP) ? Trainer Doug O'Neill had a pretty darned good day on two courses.

First he birdied the eighth hole during a Wednesday afternoon golf outing at Valhalla and then he aced the Kentucky Derby draw when Goldencents landed in the No. 8 post and was made the 5-1 third choice for Saturday's race.

"It should be perfect for him," said O'Neill, who saddled last year's winner, I'll Have Another.

"Perfect" was not the way last year's Triple Crown series ended for O'Neill and his colt. He came under intense scrutiny after another one of his horses failed a drug test and I'll Have Another was retired with a leg injury the day before the Belmont Stakes.

As for the birdie ? the highlight of an otherwise forgettable round ? he said, "That was like winning the Derby on the golf course. It was a par-3 and I just knocked it right in the middle."

Orb was made the slight 7-2 favorite over undefeated Verrazano, one of a record-tying five horses for trainer Todd Pletcher.

Trained by Shug McGaughey, Orb drew the No. 16 post in a full field of 20 horses. Four horses have won from there, most recently Animal Kingdom two years ago. McGaughey is in racing's Hall of Fame, but the 62-year-old trainer has yet to win the Derby in six previous tries.

"I think where from he is, we'll be solid," McGaughey said. "Kind of hold our position, maybe try to creep in a little bit more around the first turn, and he can kind of watch what's going on down on the inside."

Orb comes into the Derby on a four-race winning streak. He won the Florida Derby in his last start.

Pletcher was pleased about where his posse landed in the starting gate.

Wood Memorial winner Verrazano drew the No. 14 post and was the 4-1 second choice.

"We got everything we wanted," Pletcher said. "No complaints whatsoever."

There were four spots left in the gate ? including the dreaded No. 1 and No. 2 ? before Verrazano's name was called. Being in the No. 14 hole gives the colt the benefit of extra room because of the gap between his spot and No. 15, which is the start of the auxiliary gate.

Another Pletcher horse, Revolutionary, was the fourth choice at 10-1 on the morning line set by Churchill Downs oddsmaker Mike Battaglia. The colt is ridden by Calvin Borel, a three-time Derby winner famous for riding the rail. Revolutionary drew the No. 3 post, leaving Borel close to his favorite route on the track.

"Very happy," Pletcher said. "I think Calvin will be looking to go inside as soon as he could, so starting off inside was a good thing. Super Saver started from four."

Pletcher won his only Derby in 2010 with Super Saver under a rail-hugging ride by Borel.

Normandy Invasion is the fifth choice at 12-1.

The other 15 horses are all 15-1 or higher, including Pletcher's trio of Overanalyze (15-1), Palace Malice (20-1), and Charming Kitten (20-1).

Spiral Stakes winner Black Onyx drew the No. 1 post and is one of five 50-1 shots in the field. That spot has produced 12 Derby winners, tying with the No. 5 hole for the most successful post positions.

"The 1 post might not be ideal but we're going to make the best of what we can do with it," trainer Kelly Breen said. "After Saturday we're hoping to make it the most winningest post position in Kentucky Derby history."

Oxbow and Will Take Charge will be the record 46th and 47th Derby starters for Hall of Fame trainer D. Wayne Lukas, a four-time Derby winner. Both are long shots ? Will Take Charge at 20-1 and Oxbow at 30-1.

"The four I won it with I can't remember the post positions, so it must not be too important," said Lukas, who could become the oldest winning trainer in Derby history at 77.

The 21st horse on the points list is Fear the Kitten, an also eligible who would need a defection before 9 a.m. Friday, when Derby wagering opens, to get into the 1 ?-mile race.

If all 20 horses start, the total purse would be $2,199,800. The winner earns $1,439,800. Post time is 6:24 p.m. EDT.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-05-01-Kentucky%20Derby/id-f155ebfda9d444c3bdb77add2d820b53

Paul Kevin Curtis man of steel man of steel gucci mane Chicago sinkhole Panda Express illuminati

Tuesday, April 30, 2013

This Pristine Coffee Grinder Looks Like a Jet Engine

A quality grinder is an essential tool in making good coffee or espresso, but they're often known more for their utility than their beauty. The HG-One, though, is a different beast. Its sleek beauty will make you forget how much cranking is involved.

The HG-One requires good old-fashioned human strength to grind beans into fine grounds. Ironic, considering how futuristic the thing looks. Seems like annoying task to do every morning, but good design always comes at a cost.

What about quality? The grinder uses conical burrs, the standard in good grinders. But it's more than just the burr that matters. The construction must be precise, as any play or misalignment can lead to inconsistent grind size and thus sub-par coffee.

Can the HG-One deliver on that front? You'll have to plunk down about $900 to find out. But for now, might as well just sit back and enjoy the view. [HG-One Grinder via NotCot]

Source: http://gizmodo.com/this-pristine-coffee-grinder-looks-like-a-jet-engine-484341263

Florida Gulf Coast Golf Channel Andy Enfield La Salle University the voice Denny Hamlin My Chemical Romance

Protein improves efficacy of tumor-killing enzyme

Protein improves efficacy of tumor-killing enzyme [ Back to EurekAlert! ] Public release date: 30-Apr-2013
[ | E-mail | Share Share ]

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American Society for Microbiology, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells. By attaching a protein called ubiquitin to the enzyme, they were able to protect it from degradation by the cell, allowing the enzyme to complete its mission. The results indicate that ubiquitin may be a useful addition to targeted toxins.

Although researchers have been developing tumor-directed "targeted toxins" for decades, their success has been hindered by technical problems, including inadequate tumor specificity, low efficiency of delivery to the interior of the cell (also called the cytosol), and other issues. In this study, researchers from the National Institute of Allergy and Infectious Diseases sought to improve the persistence of the enzyme in the cytosol.

They created bundles of proteins designed to carry this out. The targeted toxin assembly included two components the researchers have used before in targeted toxins: the "killing" enzyme PEIII, and a set of targeting proteins called LFn that deliver the PEIII enzyme via pores to the inside of the cell. The LFn delivery system was engineered to specifically target and attach to tumor cells.

The third component in the bundle was a new addition: ubiquitin, a small protein that is normally used by cells to target waste proteins for degradation. The researchers inserted ubiquitin in between the LFn and the PEIII, then tested the bundle on mice with tumors. The idea was to use the cell's own ubiquitin-cleaving enzymes to cut the ubiquitin off and free up the PEIII enzyme once it's inside the cell.

The system worked. Tumor growth was inhibited in mice treated with targeted toxins that either carried the wild-type ubiquitin or engineered ubiquitin without lysine residues in it, a change that should prevent it from being degraded by the cell. The addition of ubiquitin enhanced the ability of the PEIII enzyme to persist inside the cell thereby enhancing its potency. And the ubiquitin didn't seem to hinder the efficiency of delivering the PEIII inside the cell.

As an added bonus, the addition of ubiquitin reduced the toxicity of the targeted toxin to non-tumor tissues.

The authors point out that the use of ubiquitin linkers shows considerable promise and could be an effective strategy for enhancing the potency of tumor-targeting toxins for use in patients. In research currently underway, they are attempting to improve on the system by making changes to the ubiquitin that allow it to unfold appropriately inside the cell.

###

mBio is an open access online journal published by the American Society for Microbiology to make microbiology research broadly accessible. The focus of the journal is on rapid publication of cutting-edge research spanning the entire spectrum of microbiology and related fields. It can be found online at http://mbio.asm.org.

The American Society for Microbiology is the largest single life science society, composed of over 39,000 scientists and health professionals. ASM's mission is to advance the microbiological sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Protein improves efficacy of tumor-killing enzyme [ Back to EurekAlert! ] Public release date: 30-Apr-2013
[ | E-mail | Share Share ]

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio, the online open-access journal of the American Society for Microbiology, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells. By attaching a protein called ubiquitin to the enzyme, they were able to protect it from degradation by the cell, allowing the enzyme to complete its mission. The results indicate that ubiquitin may be a useful addition to targeted toxins.

Although researchers have been developing tumor-directed "targeted toxins" for decades, their success has been hindered by technical problems, including inadequate tumor specificity, low efficiency of delivery to the interior of the cell (also called the cytosol), and other issues. In this study, researchers from the National Institute of Allergy and Infectious Diseases sought to improve the persistence of the enzyme in the cytosol.

They created bundles of proteins designed to carry this out. The targeted toxin assembly included two components the researchers have used before in targeted toxins: the "killing" enzyme PEIII, and a set of targeting proteins called LFn that deliver the PEIII enzyme via pores to the inside of the cell. The LFn delivery system was engineered to specifically target and attach to tumor cells.

The third component in the bundle was a new addition: ubiquitin, a small protein that is normally used by cells to target waste proteins for degradation. The researchers inserted ubiquitin in between the LFn and the PEIII, then tested the bundle on mice with tumors. The idea was to use the cell's own ubiquitin-cleaving enzymes to cut the ubiquitin off and free up the PEIII enzyme once it's inside the cell.

The system worked. Tumor growth was inhibited in mice treated with targeted toxins that either carried the wild-type ubiquitin or engineered ubiquitin without lysine residues in it, a change that should prevent it from being degraded by the cell. The addition of ubiquitin enhanced the ability of the PEIII enzyme to persist inside the cell thereby enhancing its potency. And the ubiquitin didn't seem to hinder the efficiency of delivering the PEIII inside the cell.

As an added bonus, the addition of ubiquitin reduced the toxicity of the targeted toxin to non-tumor tissues.

The authors point out that the use of ubiquitin linkers shows considerable promise and could be an effective strategy for enhancing the potency of tumor-targeting toxins for use in patients. In research currently underway, they are attempting to improve on the system by making changes to the ubiquitin that allow it to unfold appropriately inside the cell.

###

mBio is an open access online journal published by the American Society for Microbiology to make microbiology research broadly accessible. The focus of the journal is on rapid publication of cutting-edge research spanning the entire spectrum of microbiology and related fields. It can be found online at http://mbio.asm.org.

The American Society for Microbiology is the largest single life science society, composed of over 39,000 scientists and health professionals. ASM's mission is to advance the microbiological sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/asfm-pie042613.php

CMA Awards 2012 election day Electoral College map nyc marathon nyc marathon willie nelson khloe kardashian

NYC exhibition depicts ancient Buddhist caves

NEW YORK (AP) ? The China Institute Gallery has been transformed into an ancient cave, taking visitors back more than a millennium to a dazzling world where Buddhist worshippers adorned the walls with colorful frescoes, silk prayer banners and lavishly painted life-size clay sculptures.

"Dunhuang: Buddhist Art at the Gateway of the Silk Road" features a replica of an 8th century cave carved into the limestone cliffs at the edge of the Gobi Desert southeast of the oasis town of Dunhuang from 366 to about 1300.

It is one of 735 Mogao Caves constructed during what is known as the high Tang period (705-781), designed for devout Buddhists to gather and worship. Nearly every inch is covered in art, with a canopy ceiling resplendent in floral and diamond shapes. One end is filled with life-sized sculptures of a Buddha flanked by two monk disciples wearing luxuriously patterned robes, two bare-chested figures and two ferocious-looking guardians in military armor.

While there have been exhibitions that have featured individual pieces from the Mogoa Caves, this is the first exhibition in the United States to put all the elements of the cave shrines into context, said Annette Juliano, a professor of Chinese art history at Rutgers University.

It shows the "relationship between the architecture, the pictures, the subject matter and the (ritual) practices . the actual use of the cave, rather than just an abstraction," added Juliano, who visited the caves for the first time in 1980.

Many of the caves are exquisitely preserved but others are fragile due to neglect over the centuries and the conditions of the surrounding desert and sand dunes. To protect them from further erosion, tourist access is limited to several dozen caves a day that are rotated regularly.

The exhibition also features a 6th-century replica of an elaborate square altar called the Central Stupa Pillar that highlights the religious ritual of circumambulation ? an act of veneration ? in which the faithful walk clockwise around the altar that contains four niches, each holding a Buddha.

"Walking around the stupa pillar helps to empty your mind to allow visualization, to focus on the images of the Buddhas," said Juliano, who contributed an essay to the exhibition catalog.

Exact, hand-painted reproductions of wall motifs and story scenes complete the exhibition space in this gallery. Among the highlights is a Thousand Buddha pattern that covers an entire wall and is symbolic of the deity's omnipresence. Among the narrative paintings is the tale of the Deer King and his journey toward enlightenment.

Authentic silk prayer banners, a handwritten Buddhist scripture in near mint condition, a Yuan dynasty fragment of a mathematical document, small clay figurines, Persian silver coins that bear witness to foreign travelers on the Silk Road, patterned floor tiles and oil lamps used to light the dark caves round out the small two-gallery exhibition.

The Mogao Cave shrines, declared a UNESCO World Heritage Site in 1987, were largely unknown in the West until they were discovered in 1900 by a Hungarian archaeologist, Sir Aurel Stein.

Dunhuang, located at the north and south crossroads of the Silk Road, was a strategic hub of trade and religion. Stein, who made several treks through Central Asia, had heard rumors of a cave room sealed in the 11th century containing tens of thousands of manuscripts, scrolls, silk paintings and textiles dating in Chinese, Tibetan, Sanskrit and other languages.

A local caretaker had uncovered the treasure trove after discovering a crack in the wall of a corridor leading to a larger cave. It's not clear why the room was sealed, but scholars speculate they were walled up to protect them from the threat of invasion from nomadic people.

Stein was able to persuade the caretaker to sell a portion of the material in exchange for money for the cave's upkeep. In subsequent years, almost 80 percent of the contents were taken out of the country by foreign adventurers. Today, the treasures are found in various museums and libraries around the world.

The exhibition, organized by the Dunhuang Academy, runs through July 21. A second exhibition in the fall will focus on paintings and sculptures by contemporary artists inspired by the caves.

__

Online: www.chinainstitute.org

Source: http://news.yahoo.com/nyc-exhibition-depicts-ancient-buddhist-caves-063312779.html

bobbi kristina brown new edition austerity rihanna and chris brown back together pebble beach cause of whitney houston death keanu reeves

Sunday, April 28, 2013

OpenMobile ACL for webOS resurrected on Kickstarter, hopes to bring Android apps to HP Touchpad

OpenMobile ACL for webOS resurrected on Kickstarter, hopes to bring Android apps to HP Touchpad

The promise of OpenMobile's Application Compatibility Layer is enticing: seamlessly run Android apps on another operating system as if it was meant to be there. Unfortunately for fans of Palm's last hurrah, the project's webOS port died with the HP Touchpad. That won't stop dedicated fans, however -- Phoenix International Communications plans to resurrect webOS ACL. Taking the project to Kickstarter, the team is showing an early build on an HP Touchpad, seamlessly running Android apps in cards alongside native webOS applications. Phoenix hopes that a functional ACL will reduce Touchpad owner's reliance on dual-booting Android, giving them the freedom to enjoy webOS without sacrificing functionality. The team is promising a relatively short development time, thanks to OpenMobile's early work, and hopes to deliver a consumer ready build in July. But first the Kickstarter campaign will need to meet its $35,000 goal. Interested in pitching in? Check out the Kickstarter link at the source.

Filed under: ,

Comments

Source: Kickstarter

Source: http://www.engadget.com/2013/04/28/openmobile-acl-for-webos-resurrected-on-kickstarter/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

NHL lockout Honey Boo Boo pirate bay Psalms 91 once upon a time once upon a time RG3

Protesters march against first British drone base

LONDON (AP) ? Anti-war protesters are demonstrating outside a Royal Air Force base used to control drone flights over Afghanistan.

Until this week, British drones were operated only from a U.S. Air Force base in Nevada.

The Ministry of Defense announced Thursday that a new drone-operating squadron had begun operating from RAF Waddington in eastern England.

The ministry says the Reaper drones are used for "intelligence and surveillance missions," but also are equipped with missiles and bombs.

Opponents who are marching Saturday say drones make it too easy to launch deadly attacks from a distance and out of public sight.

The defense ministry says drone operators "adhere strictly to the same laws of armed conflict and are bound by the same clearly defined rules of engagement" as other RAF pilots.

Source: http://news.yahoo.com/protesters-march-against-first-british-drone-133618292.html

Paul Harvey ihop Sasquatch 2013 super bowl commercials wheres my refund Fast And Furious 6 superbowl ads